(XA663) High Throughput Experimentation Laboratory Technician

Barcelona Institute Of Science And Technology (Bist)

31 ago | Barcelona Institute Of Science And Technology (Bist) | Tarragona

The Institute of Chemical Research of Catalonia (ICIQ) is seeking a Laboratory Technician to work in the High Throughput Experimentation Unit of the Reaction Technologies Department. ICIQ is committed to performing excellent research at the frontier of knowledge in the broad area of chemistry (Catalysis, Artificial Photosynthesis, Activation of Small Molecules, Photovoltaics, Functional Molecular Assemblies and Chemical Biology, from either theoretical or experimental perspectives). The institute also aims at training the future generation of scientists by offering high-quality educational programmes to master, PhD students and postdoctoral researchers (Full details on ).

Our mission is to lead from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving citizens' quality of life in our influence area.

The candidate will work in the High Throughput Experimentation (HTE) Unit. This core facilities Unit offers a dynamic environment for a skilled chemist to support cutting-edge research through HTE. The unit is dedicated to the rapid exploration of chemical reaction space through parallel execution of microscale reactions. The reactions are then analysed using high throughput analysis methods coupled with specialized software. This systematic approach enables to speed up reaction discovery and synthetic development.

The services offered from the HTE Unit are:

1. Design and execution of screening campaigns to explore reactivity and chemical reaction space.
2. Parallel synthesis.
3. Generation of compound libraries.
4. Generation of high-quality data for AI/ML applications.
5. Scientific and technical training of researchers in HTE methodology and associated techniques.

Tasks and Responsibilities:

1. Maintenance, checking, calibration and troubleshooting of laboratory equipment (mainly GC-MS, UPLC-MS, SFC, Prep LC-MS and glove box).
2. Development of analytical methods using GC-MS/FID, UPLC-MS/DAD, SFC-DAD for compound identification and quantification in complex mixtures.
3. Development of data processing methods and data visualization workflows with HTE-analysis software to streamline analysis and interpretation of experimental results.
4. Preparation of pre-dosed reaction plates.
5. Execution of HTE screening campaigns.
6. Run preparative HPLC-MS/DAD purifications to isolate target compounds.
7. Help and teach the ICIQ researchers in the use of the Unit instrumentation.
8. Management and maintenance of the Unit reagent library.
9. Lab organization (inventory, orders, managing repairs).

Requirements:

1. BSc degree in Chemistry.
2. Chromatography knowledge and experience.
3. Organic synthesis knowledge and experience.
4. Motivation and ability to solve complex problems.
5. Advanced knowledge of Excel.
6. Good English level.
7. Organized and meticulous person.